Guide 2 — results in hand

Types of blood tests: the usual NHS tests and what each checks

Most blood tests ordered in the UK come from a short list: full blood count, urea and electrolytes, liver function, cholesterol, HbA1c, thyroid and iron. What each one checks, and what it leaves open.

Key figures

251,891
participants in the Cochrane review: general health checks did not reduce deaths[1]
+20%
more new diagnoses over six years in people offered checks, with no better outcomes[2]
82%
of critically high potassium results from GP samples in one NHS service in November 2024 were normal on repeat[3]
45 µg/L
ferritin cut-off suggested by UK gastroenterologists, above the lower limit many laboratories print[6]

A request form ticks groups, not single lines

What comes back as thirty lines is usually a handful of small groups that your GP ticked on the request form, and inside each group the lines are meant to be read against each other. Haemoglobin with MCV and ferritin. ALT with AST and GGT. Creatinine with eGFR and how much you had been drinking.

That is why reading your results from top to bottom rarely works, and why each page in this guide explains a group of tests rather than a single marker.

Why one number on its own says little

A single value outside its range, read in isolation, is the quickest route to the wrong conclusion. The same raised ALT does not mean the same thing after a bout of flu, after a heavy weekend, or after starting a new medicine.

So every page here starts from the group: which lines make it up, which one is read first, and which combinations are worth a question at your next GP appointment.

What routine blood tests show, and what they do not

Routine tests describe how a few large systems are behaving on the day of the sample: blood cells, blood sugar, kidneys, liver, thyroid, cholesterol and iron. They are not a cancer screen, they do not look for most infections, and they leave out vitamin D or B12 unless someone asked for them.

More lines do not buy more protection. A Cochrane systematic review of 17 randomised trials and 251,891 participants found that general health checks offered to adults had no effect on deaths from any cause, from cancer or from heart disease. In one of those trials, people offered checks collected 20% more new diagnoses over six years, with no change in outcomes.

Some lines go wrong for practical reasons rather than medical ones. Potassium is the best-known example: red cells damaged in transit release it into the sample on its way to the laboratory. In one NHS pathology service, 82% of critically high potassium results from GP surgeries in November 2024 turned out to be normal on a repeat sample, against 41% in August: cold weather and long journeys to the laboratory were the culprits.

Four results that are read differently today

Four lines are interpreted differently from a few years ago, which matters whenever you compare new results with older ones.

  1. CholesterolNICE does not require a fasting sample for a full lipid profile, so most cholesterol tests are now taken at any time of day. LDL may simply be missing when triglycerides are high.
  2. KidneysNICE asks laboratories to use the CKD-EPI equation to estimate kidney filtration (eGFR), and notes it has not been well validated in some ethnic groups living in the UK. Older and newer figures may not be calculated the same way.
  3. IronUK gastroenterologists note that most laboratories set the lower limit for ferritin between 15 and 30 µg/L, while a cut-off of 45 µg/L has been suggested as the best trade-off for spotting iron deficiency.
  4. ThyroidFor a raised TSH with a normal free T4, NICE suggests treatment be considered when TSH is 10 or more on two tests three months apart; below that, only a trial in adults under 65 with symptoms.

Where to start

If your results run to a long list, begin with the full blood test guide, which explains how the groups fit together and what a check-up can and cannot tell you. Then go to the group that carries your flagged lines: full blood count, urea and electrolytes, cholesterol, liver, kidneys, thyroid or iron.

The articles in this guide

PillarWhat does a full blood test include, and can your GP do one?There is no single test called a “full blood test” on an NHS request form. What comes back is a set of small groups — blood count, kidneys, liver, cholesterol, sugar — and each group is read as a whole rather than line by line.ArticleFull blood count (FBC): why your GP orders it and what it can showThree families of cells, counted and measured. A full blood count makes sense when its lines are read against each other, which is why reading it from top to bottom misses the point.ArticleUrea and electrolytes (U&Es): what the test is for and what upsets itSodium does not tell you how much salt you eat. It tells you how much water you are carrying relative to the salt already there, which is why a low sodium is usually a water problem rather than a salt one.ArticleLipid profile test: healthy levels and what happens if yours are highFour or five lines in mmol/L, and only some of them are judged against a range. The rest are read against your own risk of a heart attack or stroke over the next ten years.ArticleLiver function test (LFTs): what’s checked and what abnormal results meanMost of a liver function test does not measure how well your liver works. It measures enzymes that leak out when liver or bile duct cells are irritated, which is a different question, and the answer lies in the pattern.ArticleThyroid function tests: what TSH and free T4 show, and when treatment is offeredTSH is not a thyroid hormone, and it moves the opposite way to the gland. Most UK laboratories measure it first and only add free T4 or free T3 when it falls outside its range.ArticleKidney function blood test: what your eGFR and creatinine really meanCreatinine is a waste product, eGFR is an estimate worked out from it, and neither is a diagnosis on a single day. On a UK results sheet, the urine test that often comes with them matters just as much.ArticleIron studies: what ferritin and transferrin saturation say about your ironFerritin is your iron store, transferrin saturation is what is circulating, and the ferritin figure that counts as ‘low’ depends on whether inflammation is in the picture.

Your own results

Your blood test results, explained marker by marker

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Sources

Guidelines, consensus statements and peer-reviewed studies. Every figure on this page comes from one of them. Preprints are not cited.

  1. Systematic review

    General health checks in adults for reducing morbidity and mortality from disease

    Cochrane Database of Systematic Reviews · 2019doi:10.1002/14651858.CD009009.pub3

  2. Systematic review

    General health checks in adults for reducing morbidity and mortality from disease: Cochrane systematic review and meta-analysis

    BMJ · 2012doi:10.1136/bmj.e7191

  3. Audit, NHS pathology service

    Seasonal pseudohyperkalaemia in primary care: are there lessons to be learnt?

    Family Practice · 2026doi:10.1093/fampra/cmag035

  4. Guideline

    Cardiovascular disease: risk assessment and reduction, including lipid modification (NG238)

    National Institute for Health and Care Excellence (NICE) · 2023

  5. Guideline

    Chronic kidney disease: assessment and management (NG203)

    National Institute for Health and Care Excellence (NICE) · 2021

  6. Guideline

    British Society of Gastroenterology guidelines for the management of iron deficiency anaemia in adults

    Gut · 2021doi:10.1136/gutjnl-2021-325210

  7. Guideline

    Thyroid disease: assessment and management (NG145)

    National Institute for Health and Care Excellence (NICE) · 2019

  8. Official guidance

    Blood tests

    NHS · 2023