Guide 2 — results in hand
Types of blood tests: the usual NHS tests and what each checks
Most blood tests ordered in the UK come from a short list: full blood count, urea and electrolytes, liver function, cholesterol, HbA1c, thyroid and iron. What each one checks, and what it leaves open.
Key figures
- 251,891
- participants in the Cochrane review: general health checks did not reduce deaths[1]
- +20%
- more new diagnoses over six years in people offered checks, with no better outcomes[2]
- 82%
- of critically high potassium results from GP samples in one NHS service in November 2024 were normal on repeat[3]
- 45 µg/L
- ferritin cut-off suggested by UK gastroenterologists, above the lower limit many laboratories print[6]
A request form ticks groups, not single lines
What comes back as thirty lines is usually a handful of small groups that your GP ticked on the request form, and inside each group the lines are meant to be read against each other. Haemoglobin with MCV and ferritin. ALT with AST and GGT. Creatinine with eGFR and how much you had been drinking.
That is why reading your results from top to bottom rarely works, and why each page in this guide explains a group of tests rather than a single marker.
Why one number on its own says little
A single value outside its range, read in isolation, is the quickest route to the wrong conclusion. The same raised ALT does not mean the same thing after a bout of flu, after a heavy weekend, or after starting a new medicine.
So every page here starts from the group: which lines make it up, which one is read first, and which combinations are worth a question at your next GP appointment.
What routine blood tests show, and what they do not
Routine tests describe how a few large systems are behaving on the day of the sample: blood cells, blood sugar, kidneys, liver, thyroid, cholesterol and iron. They are not a cancer screen, they do not look for most infections, and they leave out vitamin D or B12 unless someone asked for them.
More lines do not buy more protection. A Cochrane systematic review of 17 randomised trials and 251,891 participants found that general health checks offered to adults had no effect on deaths from any cause, from cancer or from heart disease. In one of those trials, people offered checks collected 20% more new diagnoses over six years, with no change in outcomes.
Some lines go wrong for practical reasons rather than medical ones. Potassium is the best-known example: red cells damaged in transit release it into the sample on its way to the laboratory. In one NHS pathology service, 82% of critically high potassium results from GP surgeries in November 2024 turned out to be normal on a repeat sample, against 41% in August: cold weather and long journeys to the laboratory were the culprits.
Four results that are read differently today
Four lines are interpreted differently from a few years ago, which matters whenever you compare new results with older ones.
- CholesterolNICE does not require a fasting sample for a full lipid profile, so most cholesterol tests are now taken at any time of day. LDL may simply be missing when triglycerides are high.
- KidneysNICE asks laboratories to use the CKD-EPI equation to estimate kidney filtration (eGFR), and notes it has not been well validated in some ethnic groups living in the UK. Older and newer figures may not be calculated the same way.
- IronUK gastroenterologists note that most laboratories set the lower limit for ferritin between 15 and 30 µg/L, while a cut-off of 45 µg/L has been suggested as the best trade-off for spotting iron deficiency.
- ThyroidFor a raised TSH with a normal free T4, NICE suggests treatment be considered when TSH is 10 or more on two tests three months apart; below that, only a trial in adults under 65 with symptoms.
Where to start
If your results run to a long list, begin with the full blood test guide, which explains how the groups fit together and what a check-up can and cannot tell you. Then go to the group that carries your flagged lines: full blood count, urea and electrolytes, cholesterol, liver, kidneys, thyroid or iron.
The articles in this guide
Your own results
Your blood test results, explained marker by marker
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Sources
Guidelines, consensus statements and peer-reviewed studies. Every figure on this page comes from one of them. Preprints are not cited.
- Systematic review
General health checks in adults for reducing morbidity and mortality from disease
- Systematic review
- Audit, NHS pathology service
Seasonal pseudohyperkalaemia in primary care: are there lessons to be learnt?
- Guideline
Cardiovascular disease: risk assessment and reduction, including lipid modification (NG238)
- Guideline
- Guideline
- Guideline
- Official guidance